Antibiotics and antimicrobial peptides have essential differences, and antimicrobial peptides should not be confused with peptide antibiotics As an alternative to antibiotics, the development and application of antimicrobial peptides is currently a hot topic in global research on antibiotics, adjuvants, and immunostulants, attracting a large number of biotechnology companies to continue research. With the advancement of technology, the phrase "antimicrobial peptides benefit all mankind" will gradually a reality. Antibiotics are derived from microorganisms and can cause drug resistance, while antimicrobial peptides are components of the defense system of animals,, and microorganisms and do not produce drug resistance. Antibiotics bind to the cell membrane receptors of bacteria, while antimicrobial peptides disrupt the cell membrane of. The action of antimicrobial peptides does not involve specific targets and is entirely the result of the physical action of cation-anion. It can quickly microorganisms. Since the structure and charge of the bacterial surface cannot be changed, it is difficult to develop drug resistance. Adding it to feed can replace antibiotics such as chletracycline and oxytetracycline for feeding, reducing antibiotic residues in animal food.